VIEW OUR PUBLICATIONS…
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The WAVE complex in developmental and adulthood brain disorders.
Hyung-Goo Kim, Clara Berdasco, Angus C. Nairn, Yong Kim. Exp Mol Med (2025). https://doi.org/10.1038/s12276-024-01386-w
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Ahnak in the prefrontal cortex mediates behavioral correlates of stress resilience and rapid antidepressant action in mice.
Dionnet L Bhatti, Junghee Jin, Jia Cheng, Kathryn McCabe, Ko-Woon Lee, Clara Berdasco, Yu Young Jeong, Subhash C Sinha, Yong Kim. Front Mol Neurosci. 2024 May 17;17:1350716. doi: 10.3389/fnmol.2024.1350716.
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S100A10 and its binding partners in depression and antidepressant actions
Chen MX, Oh YS, Kim Y. S100A10 and its binding partners in depression and antidepressant actions. Front Mol Neurosci. 2022;15:953066. 2022. Review. PubMed PMID: 36046712; PubMed Central PMCID: PMC9423026.
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Molecular and Cellular Adaptations in Hippocampal Parvalbumin Neurons Mediate Behavioral Responses to Chronic Social Stress
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Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior.
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WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine.
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Alteration by p11 of mGluR5 localization regulates depression-like behaviors.
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APP intracellular domain-WAVE1 pathway reduces amyloid-B production.
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p11 and its role in depression and therapeutic responses to antidepressants.
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SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action.
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Signaling pathways controlling the phosphorylation state of WAVE1, a regulator of actin polymerization
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Methylphenidate-induced dendritic spine formation and DeltaFosB expression in nucleus accumbens.
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WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines.
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Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology.